Acknowledgements . . . . . . . . . .
Preface . . . . . . . . . .
Foreword by Dr. John L. Gedye . . . . . . . . . .
Introduction
by Dr. John C. Lowe . . . . . . . . . .
Section IFibromyalgia:
The New Imperative
Chapter
1.1Fall of the Rheumatology Paradigm and the New Imperative . . . .
Chapter 1.2Fibromyalgia
is Not a "Somatoform Disorder
. . . .
Section IIBackground:
Basic and Clinical Sciences
Chapter 2.1Thyroid Hormone Physiology
. . . .
Chapter 2.2Cellular Actions of Thyroid Hormones
. . . .
Chapter 2.3Genomic Actions and Molecular Biology
of Thyroid Hormones . . . .
Chapter 2.4Thyroid Hormone Deficiency
. . . .
Chapter 2.5Euthyroid Hypometabolism
. . . .
Chapter 2.6Thyroid Hormone Resistance
. . . .
|
Section III |
Interpretation
of Fibromyalgia |
|
Symptoms and Objective Findings as
Manifestations of Inadequate Thyroid
Hormone Regulation |
Section III-ASystem Mechanisms
Chapter 3.1Adrenergic System . . . .
Chapter 3.2Blood Pressure and Circulation . . . .
Chapter 3.3Connective Tissue . . . .
Chapter 3.4Fitness and Exercise Intolerance . . . .
Chapter 3.5Hypothalamic-Pituitary-Adrenal Axis . . . .
Chapter 3.6Sex Hormones: Hypothalamic-Pituitary-Gonadal Axis . . . .
Section III-BMechanisms Underlying
Particular
Signs, Symptoms and Objective Findings
Chapter 3.9
Cold and Heat Intolerance . . . .
Chapter 3.10Depression, Anxiety, and
Cognitive Dysfunction . . . .
Chapter 3.11Fatigue and Flexed Posture . . . . . . . . . .
Chapter 3.12Growth Hormone and Somatomedin C . . . .
Chapter 3.13Immune Dysregulation . . . .
Chapter 3.14Irritable Bowel Syndrome . . . .
Chapter 3.15Pain . . . .
Chapter 3.16Paresthesia . . . .
Chapter 3.17Sicca-Like Membranes and Dry Skin . . . .
Chapter 3.18Sleep Disturbance . . . .
Chapter 3.19Substance P . . . . . . . . . .
Chapter 3.20Swelling and Stiffness . . . .
Chapter 3.21Urinary Frequency and
Urgency . . . .
Section IVDiagnosis
and Assessment
Chapter 4.1Diagnosis of Fibromyalgia: Evaluation
of the
Patient’s Changing Status . . . .
Chapter 4.2Laboratory Evaluation of Thyroid Status . . . .
Chapter 4.3Symptoms, Signs, and Peripheral Indices . . . .
Chapter 4.4Adverse Effects of Excessive and Inadequate
Thyroid Hormone . . . .
Section VTreatment:
Metabolic Rehabilitation
Chapter 5.1Review of Studies: Fibromyalgia Treatments . . . .
Chapter 5.2Treatment Protocol . . . .
Chapter 5.3T4 (Thyroxine) and Combined T4/T3
Preparations:
Considerations for the Treatment of Hypothyroid Fibromyalgia . . . .
Chapter 5.4T3 (Triiodothyronine): Considerations for
the
Treatment of Fibromyalgia . . . .
Chapter 5.5Complementary Methods: Increasing Metabolic
Capacity and Decreasing Metabolic Demand . . . .
Appendices
Appendix A
Fibromyalgia Assessment Forms and Blank Line Graphs .
. . .
Appendix B
Published Papers on Fibromyalgia by Dr. John C. Lowe and Colleagues
. . . .
Appendix C
Debate with Michael Weintraub, MD . . . .
Appendix D
Conversions: T4, T3, and Desiccated
Thyroid . . . .
Glossary
Index
