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Acknowledgements . . . . . . . . . .

Preface . . . . . . . . . .

Foreword by Dr. John L. Gedye . . . . . . . . . .

Introduction by Dr. John C. Lowe . . . . . . . . . .

Section IFibromyalgia: The New Imperative

Chapter 1.1Fall of the Rheumatology Paradigm and the New Imperative . . . .

Chapter 1.2Fibromyalgia is Not a "Somatoform Disorder . . . . . . . . . .

Section IIBackground: Basic and Clinical Sciences

Chapter 2.1Thyroid Hormone Physiology . . . . . . . . . .

Chapter 2.2Cellular Actions of Thyroid Hormones
. . . . . . . . . .

Chapter 2.3Genomic Actions and Molecular Biology of Thyroid Hormones
. . .

Chapter 2.4Thyroid Hormone Deficiency . . . . . . . . . .

Chapter 2.5Euthyroid Hypometabolism . . . . . . . . . .

Chapter 2.6Thyroid Hormone Resistance . . . . . . . . . .

Section III  Interpretation of Fibromyalgia
Symptoms and Objective Findings as
Manifestations of Inadequate Thyroid
Hormone Regulation

Section III-ASystem Mechanisms

Chapter 3.1Adrenergic System . . . . . . . . . .

Chapter 3.2Blood Pressure and Circulation . . . . . . . . . .

Chapter 3.3Connective Tissue . . . . . . . . . .

Chapter 3.4Fitness and Exercise Intolerance . . . . . . . . . ..

Chapter 3.5Hypothalamic-Pituitary-Adrenal Axis . . . . . . . . . .

Chapter 3.6Sex Hormones: Hypothalamic-Pituitary-Gonadal Axis . . . . . . .


Section III-BMechanisms Underlying Particular
Signs, Symptoms and Objective Findings

Chapter 3.9Cold and Heat Intolerance . . . . . . . . . .

Chapter 3.10Depression, Anxiety, and Cognitive Dysfunction . . . . . . . . . .

Chapter 3.11Fatigue and Flexed Posture . . . . . . . . . .

Chapter 3.12Growth Hormone and Somatomedin C . . . . . . . . . .

Chapter 3.13Immune Dysregulation . . . . . . . . . .

Chapter 3.14Irritable Bowel Syndrome . . . . . . . . . .

Chapter 3.15Pain . . . . . . . . . .

Chapter 3.16Paresthesia . . . . . . . . . .

Chapter 3.17Sicca-Like Membranes and Dry Skin . . . . . . . . . .

Chapter 3.18Sleep Disturbance . . . . . . . . . .

Chapter 3.19Substance P . . . . . . . . . .

Chapter 3.20Swelling and Stiffness . . . . . . . . . .

Chapter 3.21Urinary Frequency and Urgency . . . . . . . . . .

Section IVDiagnosis and Assessment

Chapter 4.1Diagnosis of Fibromyalgia and Evaluation of the
Patient’s Changing Status . . . . . . . . . .

Chapter 4.2Laboratory Evaluation of Thyroid Status . . . . . . . . . .

Chapter 4.3Symptoms, Signs, and Peripheral Indices . . . . . . . . . .

Chapter 4.4Adverse Effects of Excessive and Inadequate
Thyroid Hormone . .

Section IVTreatment: Metabolic Rehabilitation

Chapter 5.1Review of Studies: Fibromyalgia Treatments . . . . . . . . . .

Chapter 5.2Treatment Protocol . . . . . . . . . .

Chapter 5.3T4 (Thyroxine) and Combined T4/T3 Preparations:
Considerations for the Treatment of Hypothyroid Fibromyalgia . . . . . . . . . .

Chapter 5.4T3 (Triiodothyronine): Considerations for the
Treatment of Fibromyalgia . . . . . . . . . .

Chapter 5.5Complementary Methods: Increasing Metabolic
Capacity and Decreasing Metabolic Demand . . . . . . . . . .

Appendices

Appendix A

Fibromyalgia Assessment Forms and Blank Line Graphs . . . . . . . . . .

Appendix B

Published Papers on Fibromyalgia by Dr. John C. Lowe and Colleagues . . . .

Appendix C

Debate with Michael Weintraub, M.D. . . . . . . . . . .

Appendix D

Conversions: T4, T3, and Desiccated Thyroid . . . . . . . . . .

Glossary

Index


McDowell Homepage | Book Homepage | Readers' Comments |
About the Book
| Five Sections of the Book | Dr. Lowe's "Introduction" to the Book |
Table of Contents
| Cover Illustrations | A Word About the Price |
www.drlowe.com
| Interviews with Dr. Lowe |  Customer Service | To Order |